Jun Liu, Prof. Ph.D. (Chem. Eng.)
Professor (Biomass-based composites and 3D printing)
Jiangsu University
Biofuels Institute
School of the Environment and Safety Engineering
Xuefu Rode 301,
Zhenjiang, 212013, China
Phone +86 (0)511 88796122
Mobile +86 18651271662
E-mail junliu115142@hotmail.com
Website http://junliu115142.wixsite.com/mysite
CV
Research interest
Driven by the global trend in the sustainable economy development and environmental concerns, the exploring of plant-derived biomaterials or biocomposites for potential biomedical and/or pharmaceutical applications has received tremendous attention. The inherent properties of nanocelluloses, such as nontoxicity, biocompatibility, biodegradability, excellent structural strength and stiffness, and thermal stability endow them good candidates for biomedical applications such as medical implants, tissue engineering, wound healing/dressing, and drug delivery.
Keywords: 3D printing, Biorefinery, Wood and paper chemistry, Nanocellulose, Hemicellulose, Polysaccharides, Biomaterials, Biomedical application, Tissue engineering, Wound healing/dressing, Drug delivery...
Skills
HPLC
SEM
TEM
AFM
GC/GC-MS
LC/LC-MS(n)
MALDI/ESI-MS(n)
NMR
FT-IR
3D printing
Research experiences
09.2012 -09.2016
Supervisor: Professor Stefan Willför, Docent, Dr. Chunlin Xu
Project:
1) Development of processes to produce nanofibrillated fibers (NFCs) in a novel biorefinery concept for potential biomedical applications.
2) Development of a methodology integrating enzymatic, chromatographic and mass spectrometric approaches to unravel the complex molecular structure of plant polysaccharide derivatives.
09.2010 – 06.2012
Supervisor: ProfessorHuiren Hu
Project:
1) Study on the Application of Cellulase for Fiber Modification and its Mechanism
2) Fiber Characteristics and Wet-end Chemical Performance ofHigh Yield Pulp
International Scientific and Technological Joint Project of China and Canada (Grant No. 2008DFA91290 of the Ministry of Science and Technology of China)
09.2009 – 09.2010
Supervisor: ProfessorHuiren Hu
Project: Using of Chemo-enzymatic Method to Control the DCS in the White-water Circulation System of the Mechanical Pulping and Papermaking Process
National Nature Science Foundation of China (Grant No. 30771694); Tianjin Science and Technology Development Planning Program (Grant No. 06TXTJJC14302)
Academic qualification
09.2012-09.2016
Ph.D. in Chemical Engineering
Johan Gadolin Process Chemistry Centre,
c/o Laboratory of Wood and Paper Chemistry,
Åbo Akademi University, Åbo/Turku, Finland
Research areas: Plant-based biomaterials (nanocellulose, hemicellulose) for biomedical application; Structural analysis of polysaccharides and derivatives
09. 2009 - 03. 2012
Master of Science in Engineering
Tianjin Key Laboratory of Pulp and Paper
Tianjin University of Science & Technology, Tianjin, P. R. China
Major: Material Science and Chemical Engineering
Research subject of the master thesis: Application of Biotechnology in Pulping and Papermaking Process
09. 2005 - 07. 2009
Bachelor of Science in Engineering
Tianjin University of Science & Technology, Tianjin, P. R. China
Major: Material Science and Chemical Engineering
Research subject of the bachelor thesis: Control of DCS in White-water of HYP via Chemo-enzymatic Approach
International mobility
06.2016-07.2017
Host: Professor Albert Mihranyan, Nano Technology and Functional Materials, Department of Engineering Sciences, Uppsala University, Uppsala, Sweden.
Project: Leachable (1→3)-β-D-glucan from Cladophorales Green Algae nanocellulose and their proinflammatory effect upon biomedical application
04.2015-07.2015
Host: Dr. Kristin Syverud and Dr. Gary Chinga-Carrasco, Paper and Fibre Research Institute (PFI), Trondheim, Norway.
Project: All-polysaccharides biocomposites consisted of nanofibrillated cellulose and hemicellulose towards biomedical applications
10.2014
Host: Dr. Francisco Vilaplana, Division of Glycoscience/KTH Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden
Project: Integrated enzymatic, chromatographic and mass spectrometric approaches unravel the complex molecular structure of plant polysaccharide derivatives
01.2013-04.2013
Host: Dr. Francisco Vilaplana, Division of Glycoscience/KTH Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden
Project: Integrated enzymatic, chromatographic and mass spectrometric approaches unravel the complex molecular structure of plant polysaccharide derivatives
Publications （Check the latest publications on Google Scholar or ResearchGate）
1. Jun Liu, Stefan Willför, Albert Mihranyan. On Importance of Impurities, Potential Leachables and Extractables in Nonocellulose for Biomedical Use. Biomacromolecules, submitted, 2016.
2. Jun Liu, Ann-Sofie Leppänen, Victor Kisonen, Stefan Willför, Chunlin Xu, Francisco Vilaplana. Structural analysis of galactoglucomannan and its chemical derivatives using chromatography and mass spectrometry. submitted 2016.
3. Markus Peurla, Peter Kunnas, Jussi Kauppila, Antti Viinikanoja, Sauli Haataja, Rose-Marie Latonen, Patrycja Bober, Chunlin Xu, Jun Liu, Lauri Pelliniemi, Carita Kvarnström. Improved image contrast in low voltage transmission electron microscopy by using graphene oxide sample support. Journal of Applied Physics, under review 2016.
4. Wenyang Xu, Henrik Grénman, Jun Liu, Dennis Kronlund, Bin Li, Jouko Peltonen, Stefan Willför, Anna Sundberg, Chunlin Xu. Preparation of cellulose nanocrystals by mild oxalic acid-catalyzed hydrolysis. ChemNanoMat, submitted, 2016.
5. Kajsa Markstedt, Wenyang Xu, Jun Liu, Chunlin Xu, Paul Gatenholm. Synthesis of tunable hydrogels based on O-Acetyl-Galactoglucomannan from Norway Spruce. Carbohydrate Polymers, in press, 2016.
6. Jun Liu, Gary Chinga-Carrasco, Fang Cheng, Wenyang Xu, Stefan Willför, Kristin Syverud, Chunlin Xu. Hemicellulose-reinforced nanocellulose hydrogels for wound healing application. Cellulose, 2016, 23:3129–3143.
7. Jun Liu, Victor Kisonen, Stefan Willför, Chunlin Xu, Francisco Vilaplana. Profiling the substitution pattern of xyloglucan derivatives by integrated enzymatic hydrolysis, hydrophilic-interaction liquid chromatography and mass spectrometry. Journal of Chromatography A, 2016, 1463:110-120.
8. Jun Liu, Fang Cheng, Henrik Grénman, Steven Spoljaric, Jukka Seppälä, John Eriksson, Stefan Willför, and Chunlin Xu. Development of nanocellulose scaffolds with tunable structures to support 3D cell culture. Carbohydrate polymers, 2016, 148:259-271.
9. Jun Liu, Stefan Willföra, Chunlin Xu. A review of bioactive polysaccharides: biological activities, functionalization, and biomedical applications. Bioactive Carbohydrates and Dietary Fibre, 2015, 5(1):31-61.
10. Xiaoju Wang, Fang Cheng, Jun Liu, Jan-Henrik Smått, David Gepperth, Mika Lastusaari, Chunlin Xu1, Leena Hupa. Biocomposites of copper-containing mesoporous bioactive glass and nanofibrillated cellulose for chronic wound healing. Acta Biomaterialia, 2016, 46:286-298.
11. Bin Li, Wenyang Xu, Dennis Kronlund, Anni Määttänen, Jun Liu, Stefan Willför, Hongyan Mou, Xindong Mu, Chunlin Xu. Cellulose nanocrystals prepared via formic acid hydrolysis followed by TEMPO-mediated oxidation. Carbohydrate Polymers, 2015, 133: 605-612.
12. Camila Honorato, Vinay Kumar, Jun Liu, Hanna Koivula, Chunlin Xu, Martti Toivakka. Transparent nanocellulose-pigment composite films. Journal of Materials Science, 2015, 50(22):1-10.
13. Daniel Dax, M. Soledad Chávez Bastidas, Camila Honorato, Jun Liu, Steven Spoljaric, Jukka Seppälä, Regis T. Mendonça, Chunlin Xu, Stefan Willför, Julio Sánchez. Tailor-made hemicellulose-based hydrogels reinforced with nanofibrillated cellulose. Nordic Pulp and Paper Research Journal, 2015, 30(3):373-384.
14. Dimitar Valtakari, Jun Liu, Vinay Kumar, Chunlin Xu, Martti Toivakka, Jarkko J Saarinen. Conductivity of PEDOT:PSS on spin-coated and drop cast nanofibrillar cellulose thin films. Nanoscale Research Letters, 2015, 10:386.
15. Jun Liu, Risto Korpinen, Kirsi S. Mikkonen, Stefan Willför, and Chunlin Xu. Nanofibrillated cellulose originated from birch sawdust after sequential extractions – a new route of developing polymeric materials in forest biorefinery. Cellulose, 2014 21(4):2587–2598
16. Patrycja Bober, Jun Liu, Kirsi S. Mikkonen, Petri Ihalainen, Markus Pesonen, Carme Plumed-Ferrer, Atte von Wright, Tom Lindfors, Chunlin Xu, Rose-Marie Latonen. Biocomposites of nanofibrillated cellulose, polypyrrole and silver nanoparticles with electroconductive and antimicrobial properties. Biomacromolecules, 2014, 15(10): 3655-3663.
17. Ann-Sofie Leppänen, Chunlin Xu, Jun Liu, Xiaoju Wang, Markus Pesonen, Stefan Willför. Anionic polysaccharides as templates for the synthesis of conducting polyaniline and as structural matrix for conducting biocomposites. Macromol Rapid Commun, 2013, 34(13):1056-1061.
18. Jun Liu, Huiren Hu. The Role of cellulose binding domains in the adsorption of cellulases onto fibers and its effect on the enzymatic beating of bleached kraft pulp. Bioresources, 2012, 7(1): 878-892.
19. Jun Liu, Huiren Hu, Jianfeng Xu, and Yangbing Wen. Optimizing enzymatic pretreatment of recycled fiber for improving its draining ability using response surface methodology. BioResources, 2012, 7(2):2121-2140.
Book/Book Chapter
1. Jun Liu, Stefan Willför, Chunlin Xu. Tunning microscopic and mechanical properties of bio-based aerogels. Biobased aerogels: Polysaccharide and protein basedmaterials. Editor: Sabu Thomas, Laly A. Pothan and Rubie Mavelil-Sam. Royal Society of Chemistry.
Conference proceedings
1. Jun Liu, Ann-Sofie Leppänen, Patrycja Bober, Xiaoju Wang, Tom Lindfors, Rose-Marie Latonen, Stefan Willför, Chunlin Xu. Nanocellulose acting as templates for synthesis of conducting polymers and in situ formation of bicomposites. International Electromaterials Science Symposium, proceedings abstracts, North Wollongong, Australia, February 7th-10th, 2017.
2. Jun Liu, Xiaoju Wang, Fang Cheng, Gary Chinga-Carrasco, Kristin Syverud, Stefan Willför, Chunlin Xu. Nanocellulose-Based Scaffolds Torwards Medical Applications. The 1st International Symposium on Nanocellulosic Materials, proceedings abstracts, Hangzhou, China, May 20-21, 2017.
3. Chunlin Xu, Jun Liu, Xiaoju Wang, Fang Cheng, Gary Chinga-Carrasco, Kristin Syverud, Stefan Willför. Nanocellulose-based scaffolds with tunable structures to support 3D cell culture. International Conference on Nanotechnology for Renewable Materials, proceedings abstracts, Grenoble, France, June 13th-16th, 2016.
4. Antonio Martínez-Abad, Jun Liu, Chunlin Xu, Francisco Vilaplana. Pattern of glycosyl and acetyl substitutions in spruce hemicelluloses using glycomic approaches. EWLP 2016, 14th European Workshop on Lignocellulosics and Pulp, Proceeding, Autrans, France, June 28th-30th, 2016.
5. Chunlin Xu, Jun Liu, Xiaoju Wang, Fang Cheng, Gary Chinga-Carrasco, Kristin Syverud, Stefan Willför. Nanocellulose-based scaffolds with tunable structures to support 3D cell culture. International Conference on Nanotechnology for Renewable Materials. Grenoble, France, June 13th-16th 2016.
6. Jun Liu, Fang Cheng, Stefan Willför, Chunlin Xu. Nanocellulose films and aerogels with tunable structures as matrix for cellular processes in tissue engineering. EPNOE 2015, the 4th EPNOE International Polysaccharide Conference, Proceeding abstracts, Warsaw, Poland, October 19th-22th, 2015.
7. Martinez-Abad, Andrea C Ruthes, Jun Liu, Chunlin Xu, Lauren S. McKee, Vincent Bulone, Francisco Vilaplana. Glycomic approaches to unravel the intramolecular substitution patten of hemicellulose. EPNOE 2015, the 4th EPNOE International Polysaccharide Conference, Proceeding abstracts, Warsaw, Poland, October 19th-22th, 2015.
8. Chunlin Xu, Jun Liu, Patrycja Bober, Tom Lindfors, Rose-Marie Latonen. Electroconductive and antimicrobial composite films of nanocellulose, polypyrrole and silver nanoparticles. ISWFPC 2015, the 18th International Symposium on Wood, Fibreand Pulping Chemistry, Proceedings, Vienna, Austria, September 9th-11th 2015.
9. Jun Liu, Fang Cheng, Stefan Willför, Chunlin Xu. Tailoring wood cellulose to nanocomposites with controlled structure towards wound healing applications. The 8thCALSIF (Chinese Association of Life Scientists in Finland) annual meeting, Proceeding abstracts, Helsinki, Finland, November 29th, 2014.
10. Jun Liu, Chunlin Xu, Stefan Willför, Francisco Vilaplana. Structural elucidation of plant cell wall polysaccharides and their derivatives using chromatographic and mass spectrometric techniques. EWLP 2014, 13th European Workshop on Lignocellulosics and Pulp, Proceeding, Seville, Spain, June 24th-27th, 2014.
11. Chunlin Xu, Ann-Sofie Leppänen, Jun Liu, Patrycja Bober, Xiaoju Wang, Tom Lindfors, Rose-Marie Latonen, Stefan Willför. Nanofibrillated cellulose prepared from TEMPO oxidation acting as templates for synthesis of conducting polymers and in situ formation of biocomposites. EWLP 2014, the 13th European Workshop on Lignocellulosics and Pulp, Proceedings, Seville, Spain, August 24th-27th, 2014.
12. Francisco Vilaplana, Jun Liu, Lauren S. McKee, Chunlin Xu, Rosana Moriana, Monica EK. Glycomic tools for the structural characterization of hemicelluloses: Impact on their exploitation for novel-carbohydrate-based materials. POLYMAR 2013, International Conference in Polymers with special Focus in Early Stage Researchers, Proceeding abstracts, Crucero por el Mediteeráneo, Spain, November 8th-12th, 2013.
13. Jun Liu, Risto Korpinen, Kirsi S. Mikkonen, Stefan Willför, and Chunlin Xu. Nanofibrillated cellulose originated from birch sawdust after sequential extractions – a new route of developing polymeric materials in forest biorefinery. EPNOE 2013, the 3rdEPNOE International Polysaccharide Conference, Proceeding abstracts, Nice, France, October 21th-24th, 2013.
14. Jun Liu, Huiren Hu. Use of cellulase for improving the beatability of PRC-APMP. International Mechanical Pulping Conference, Proceedings, Xi’an, China, June 27th-29th, 2011, P236-239.
15. Jun Liu, Huiren Hu. Treatment of NBKP with cellulase to reduce the refining energy consumption in production of grease proof paper. The 2011 International Conference on Chemical Engineering and Advanced Materials (CEAM 2011), Proceedings, Chansha, China, May 28th-30th, 2011, Vol 236-238, pp.1379-1384.
16. Jun Liu, Huiren Hu. Combined enzyme and chemical fixing agent to control DCS in papermaking white water. Environmental Pollution and Public Health (EPPH2011), Proceedings, Wuhan, China, May 10th-12th, 2011, Vol 2, 978-1-4244-5089-2/11, pp.1-4.
17. Sha Yang, Huiren Hu, Jun Liu. Combining pectinase and chemical additives to control dissolved and colloidal substances in HYP. The 4th International Symposium on Emerging Technologies of Pulping and Papermaking, Proceedings, Guangzhou, China, August 8th-10th 2010, pp.933-936.
18. Jun Liu, Huiren Hu, Sha Yang. Combined enzymatic and chemical control agent methods to control DCS in APMP. The 4th International Symposium on Emerging Technologies of Pulping and Papermaking, Proceedings, Guangzhou, China, August 8th-10th, 2010, pp.941-944.
Part-time journal reviewer for:
1. Carbohydrate Polymers,
2. BioResources
3. Trends in Food Science & Technology
4. Green Chemistry Letters and Reviews
Other research activities and trainings
1. December, 2014. Research visit at Polymer Technology, Department of Biotechnology and Chemical Technology, Aalto University School of Chemical Technology, Espoo, Finland.
2. March, 2014. Research visit at Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland.
3. December, 2012. Research visit at Department of Food and Environmental Sciences, University of Helsinki, Helsinki, Finland.
4. June, 2011. Directing the test of chemicals of Tianjin Yutong Chemical Assistant CO., LTD at Shanxi Qiangwei paper CO., LTD., Shanxi, China.
5. July, 2010. Research visit for a pilot test at Tianjin Yutong Chemical Assistant CO., LTD.
6. July, 2008. Internship at Huatai Group, Shandong, China.
7. June, 2007. Cognition training at the Tianjin Light Industry Machinery Factory and Tianjin Zhongchao Paper industry CO., LTD., Tianjin China.
Grants, awards, and honours
1. Postdoc Scholarship granted by Olle Engquist Byggmästare Foundation and Bo Rydins Foundation for Academic Research, Uppsala University, 2016-2017, Sweden.
2. Scholarship granted by Graduate School in Chemical Engineering (GSCE), Åbo Akademi University, 2013-2016, Finland.
3. Scholarship granted by China Scholarship Council (CSC), 2012-2016, China.
4. Excellent Master Thesis & Outstanding Graduate, Tianjin University of Science & Technology, China, 2012.
5. Ph.D. graduate with honours, Åbo Akademi University, September 2016, Finland.